Prognostic Factors for Visual Outcomes in Acute Anterior Optic Neuritis Using Optical Coherence Tomography

Purpose: To identify the clinical characteristics and predictors of visual outcomes in acute anterior optic neuritis patients treated with high-dose steroid pulse therapy using spectral domain optical coherence tomography (SD-OCT).Methods: In this study, medical records 34 intravenous followed-up for at least 3 months were retrospectively reviewed. The divided into two groups based on final best-corrected acuity (BCVA); group 1 (n = 23) had a BCVA ≥20/32, while 2 11) <20/32. Clinical parameters obtained SD-OCT evaluated to factors influencing outcome.Results: There no statistically significant differences or demographic data between groups. Peripapillary retinal nerve fiber layer (pRNFL) swelling initial presentation was less common (p 0.015), time pRNFL thickness stabilization longer 0.016), 1. Multivariate logistic regression demonstrated better whom took longer, as well those smaller reduction macular ganglion cell-inner plexiform (mGCIPL) thickness, without recurrence 0.002, 0.016, 0.035, respectively).Conclusions: Intravenous much improved long-term delayed stabilization, mGCIPL reduction, recurrence. This suggests that inner after may serve biomarkers treatment neuritis.